Friday, December 25, 2009
Post: Baby Boomers Patrick Swayze was in the Fight!
News like this always saddens me. It reminds me of the valiant fight that my sister went through 7 years ago with
Pancreatic cancer. Yes, it is a killer now, but with more research and early detection perhaps it doesn't have to a death sentence. Consider a contribution to http://pancan.org
September 14, 2009
Dear Friends,
The staff of the Pancreatic Cancer Action Network, its...
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Tuesday, November 24, 2009
Post: Research From Washington University, Medical Department In The Area Of Pancreatic Cancer Described
Mesothelin is a glycoprotein expressed on normal mesothelial cells and is overexpressed in several histologic types of tumors including pancreatic adenocarcinomas. A soluble form of mesothelin has been detected in patients with ovarian cancer and malignant mesothelioma, and has prognostic value, scientists in the United States report....
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Monday, November 23, 2009
Post: Oral COTI-2 Is Effective As A Single Agent And In Combination With Gemcitabine In An Animal Model Of Human Pancreatic Cancer
Critical Outcome Technologies Inc. (COTI) (TSX VENTURE: COT) announced positive results today from animal experiments carried out at a prominent Canadian cancer research facility. This new series of experiments adds to the already impressive data package for COTI-2, demonstrating efficacy as a single agent and in combination with first line therapies with low toxicity in seven different animal models of human cancers....
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Monday, November 16, 2009
Post: Data On Pancreatic Cancer Published By Researchers At Technical University Of Munich
According to recent research from Munich, Germany, Chronic pancreatitis (CP) and pancreatic cancer (PCa) are characterized by intrapancreatic neuropathic alterations, including increased neural density and hypertrophy, pancreatic neuritis and neural invasion (NI) by cancer cells in PCa. The aim of this study was to identify the influence of these neuropathic changes on the quality of pancreatic innervation, intrapancreatic glia, and visceral pain....
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Wednesday, November 11, 2009
Post: Rare pancreatic cancer patients may live longer when treated with radiation therapy
Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors (PNTs), despite such tumors being commonly considered resistant to radiation therapy. (2009-11-23)...
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Monday, November 9, 2009
Post: Discovery offers potential new pancreatic cancer treatment
Tiny particles that can carry drugs and target cancer cells may offer treatment hope for those suffering with pancreatic cancer. New research to be presented in November at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting in Los Angeles reveals that tumor-penetrating microparticles (TPM) have been specifically designed to break through hard-to-infiltrate barriers and deliver drugs more effectively and efficiently than the standard form of chemotherapy such as those inj...
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Sunday, November 8, 2009
Post: Hepatitis B does not increase risk for pancreatic cancer
A Henry Ford Hospital study found that hepatitis B does not increase the risk for pancreatic cancer - and that only age is a contributing factor. (2009-11-02)...
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Friday, November 6, 2009
Post: Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. (2009-09-24)...
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Thursday, November 5, 2009
Post: Endothelin-1 inhibitors in chronic pancreatitis
Fibrosis is a key feature of chronic pancreatitis and pancreatic cancer. The extensive deposition of extracellular matrix proteins fosters the development of an exocrine and endocrine organ insufficiency, and accelerates progression of the tumour. (2009-09-17)...
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Tuesday, November 3, 2009
Post: MicroRNAs circulating in blood show promise as biomarkers to detect pancreatic cancer
A blood test for small molecules abnormally expressed in pancreatic cancer may be a promising route to early detection of the disease. (2009-09-08)...
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Sunday, November 1, 2009
Post: Taking the Needle's Sting Out of Diabetes
Found in 30% of all human cancer tumors, the Ras protein literally "drives cells crazy," says Prof. Yoel Kloog, the dean of the Faculty of Life Sciences at Tel Aviv University. Prof. Kloog was the first in the world to develop an effective anti-Ras drug against pancreatic cancer, currently in clinical trials. (2009-08-11)...
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Friday, October 30, 2009
Post: New Tool May Help with Early Detection of Deadly Pancreatic Cancer
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. (2009-08-04)...
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Tuesday, October 27, 2009
Post: Rare pancreatic cancer patients may live longer when treated with radiation therapy
Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors (PNTs), despite such tumors being commonly considered resistant to radiation therapy. (2009-11-23)...
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Sunday, October 25, 2009
Post: Discovery offers potential new pancreatic cancer treatment
Tiny particles that can carry drugs and target cancer cells may offer treatment hope for those suffering with pancreatic cancer. New research to be presented in November at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting in Los Angeles reveals that tumor-penetrating microparticles (TPM) have been specifically designed to break through hard-to-infiltrate barriers and deliver drugs more effectively and efficiently than the standard form of chemotherapy such as those inj...
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Saturday, October 24, 2009
Post: Hepatitis B does not increase risk for pancreatic cancer
A Henry Ford Hospital study found that hepatitis B does not increase the risk for pancreatic cancer - and that only age is a contributing factor. (2009-11-02)...
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Thursday, October 22, 2009
Post: Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. (2009-09-24)...
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Wednesday, October 21, 2009
Post: Endothelin-1 inhibitors in chronic pancreatitis
Fibrosis is a key feature of chronic pancreatitis and pancreatic cancer. The extensive deposition of extracellular matrix proteins fosters the development of an exocrine and endocrine organ insufficiency, and accelerates progression of the tumour. (2009-09-17)...
Read More
Monday, October 19, 2009
Post: MicroRNAs circulating in blood show promise as biomarkers to detect pancreatic cancer
A blood test for small molecules abnormally expressed in pancreatic cancer may be a promising route to early detection of the disease. (2009-09-08)...
Read More
Saturday, October 17, 2009
Post: Taking the Needle's Sting Out of Diabetes
Found in 30% of all human cancer tumors, the Ras protein literally "drives cells crazy," says Prof. Yoel Kloog, the dean of the Faculty of Life Sciences at Tel Aviv University. Prof. Kloog was the first in the world to develop an effective anti-Ras drug against pancreatic cancer, currently in clinical trials. (2009-08-11)...
Read More
Thursday, October 15, 2009
Post: New Tool May Help with Early Detection of Deadly Pancreatic Cancer
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. (2009-08-04)...
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Sunday, October 11, 2009
Post: Is there anyway my friend can get funding for her pancreatic cancer treatment?
lavalamppp asked: My friend was diagnosed with pancreatic cancer today and lives in Sandiego, California.
She can’t afford to pay for the cancer treatment.
Is there any way she can get funding for her treatment?
Technorati Tags: Cancer Treatment, Pancreatic Cancer, Sandiego California
...
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Saturday, September 26, 2009
Post: Texas Monthly - In 1994 caustic stand-up comic Bill Hicks was knocking on stardom's door when he died of pancreatic cancer at the age of 32
November 1, 2004 -- 1
In 1994 caustic stand-up comic BILL HICKS was knocking on stardom's door when he died of pancreatic cancer at the age of 32. Ten years later,......
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Thursday, September 24, 2009
Post: Hepatitis B does not increase pancreatic cancer risk
A Henry Ford Hospital study observed that hepatitis B does not increase the risk for pancreas cancer and that only age is a contributing factor. The results contradict a prior study in 2008 that suggested a link between pancreas cancer and prior hepatitis B infection. Hepatitis B is an inflammation of the liver caused by a viral infection........ ...
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Wednesday, September 23, 2009
Post: Progress in Pancreatic cancer treatment
For the first time scientists have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreas cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. Dr Davide Melisi told Europe's largest cancer congress, ECCO 15 ESMO 34 [1], in Berlin today (Thursday 24 September) that resistance to chemotherapy was the greatest challenge to treating pancreas cancer........ ...
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Tuesday, September 22, 2009
Post: metformin reduces risk of pancreatic cancer
Taking the most commonly-prescribed anti-diabetic drug, metformin, reduces an individual's risk of developing pancreas cancer by 62 percent, as per research from The University of Texas M. D. Anderson Cancer Center, reported in the Aug. 1 issue of Gastroenterology "This is the first epidemiological study of metformin in the cancer population, and it offers an exciting direction for future chemoprevention research for a disease greatly in need of both therapy and prevention strategies," said Don...
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Monday, September 21, 2009
Post: Smoking increases risk of metastatic pancreatic cancer
Smoking has once again been implicated in the development of advanced cancer. Exposure to nicotine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, as per scientists from the Kimmel Cancer Center at Jefferson. Their study was reported in the August edition of the journal Surgery....... ...
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Sunday, September 20, 2009
Post: Herbal extra to against pancreatic cancer
An herb recently found to kill pancreas cancer cells also appears to inhibit development of pancreas cancer as a result of its anti-inflammatory properties, as per scientists from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009 in Denver. (Abstract #494)........ ...
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Saturday, September 19, 2009
Post: Finding pancreatic cancer early
A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers and instead begin a 7,000-hour slog through a compendium of 50,000 scientific articles already published to assemble, decode and analyze the molecules that might herald the furtive presence of pancreas cancer........ ...
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Friday, September 18, 2009
Post: Determining Risk for Pancreatic Cancer
In the latest clinical trial for a technique to detect pancreas cancer, scientists found they could differentiate cells that are malignant from those that are benign, pre-malignant, or even early stage indicators called mucinous cystic lesions. Pancreas cancer is dangerous to screen for, yet deadly if ignored. The pancreas is extremely sensitive--biopsies can lead to potentially fatal complications--but with few symptoms, the cancer is commonly detected too late........ ...
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Thursday, September 17, 2009
Post: Genes and pancreatic cancer
Abnormalities in genes that repair mistakes in DNA replication may help identify people who are at high risk of developing pancreas cancer, a research team from The University of Texas M. D. Anderson Cancer Center reports in the Jan. 15 issue of Clinical Cancer Research Defects in these critical DNA repair genes may act alone or in combination with traditional risk factors known to increase an individual's likelihood of being diagnosed with this very aggressive type of cancer........ ...
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Wednesday, September 16, 2009
Post: New gene to predict outcome in pancreatic cancer
Variations in mismatch repair genes can help predict therapy response and prognosis in patients with pancreas cancer, as per research from The University of Texas M. D. Anderson Cancer Center presented today in advance of the American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium........ ...
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Tuesday, September 15, 2009
Post: Hepatitis C May Increase Pancreatic Cancer Risk
A newly released study shows that infection with hepatitis C virus (HCV) increases a person's risk for a highly fatal cancer of the biliary tree, the bile carrying pathway between the liver and pancreas. This finding is in the recent issue of Hepatology, a journal published by John Wiley and Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (www.interscience.wiley.com)........ ...
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Monday, September 14, 2009
Post: Radiation Before Surgery Improves Pancreatic Cancer Outcomes
Pancreas cancer is one of the deadliest and most difficult to treat cancers. Now, in a major step forward, scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have shown that administering radiation treatment previous to surgery nearly doubles survival in pancreas cancer patients with operable tumors........ ...
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Saturday, September 12, 2009
Post: Hepatitis B exposure and pancreatic cancer
HOUSTON - In a first-of-its-kind finding, scientists at The University of Texas M. D. Anderson Cancer Center have discovered that exposure to the hepatitis B virus (HBV) may increase the risk of pancreas cancer. The study, reported in the Oct. 1 edition of the Journal of Clinical Oncology, also suggests that patients with this lethal form of cancer treated with chemotherapy may face danger of reactivation of their HBV........ ...
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Friday, September 11, 2009
Post: Prevention and treatment of pancreatic cancer
A number of gastrointestinal tumors, including pancreas cancer, have been shown to overexpress the EGFR. The overexpression of EGFR correlates with rapidly progressive disease and poor prognosis. Targeting EGFR pathway as a potential therapeutic strategy for pancreas cancer has been developed. Erlotinib is a small molecule tyrosine kinase inhibitor that efficiently blocks EGFR. Preliminary results of phase III trial in pancreas cancer revealed an improvement in survival with the addition of erl...
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Thursday, September 10, 2009
Post: New drug substantially extends survival in pancreatic cancer
A new form of chemotherapy that destroys new blood vessels that grow around tumors has produced excellent results in a phase II trial of patients with inoperable pancreas cancer, scientists report at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm. European researchers led by Prof. Matthias Lhr from the Karolinska Institute reviewed the efficacy and safety of three different doses of cationic lipid complexed paclitaxel (EndoTAG-1) administered twice weekly, in...
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Tuesday, September 1, 2009
Post: Pancreatic cancer: The silent killer
There are 7,700 cases of pancreatic cancer a year and the survival rates are so low. Learn about its symptoms, treatment and help donate to find a cure, all ahead of the first ever Pancreatic
Cancer Awareness Week, November 16-22.
...
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Sunday, August 30, 2009
Post: Radiation Before Surgery Improves Pancreatic Cancer Outcomes
Pancreas cancer is one of the deadliest and most difficult to treat cancers. Now, in a major step forward, scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have shown that administering radiation treatment previous to surgery nearly doubles survival in pancreas cancer patients with operable tumors........ ...
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Friday, August 28, 2009
Post: Hepatitis B exposure and pancreatic cancer
HOUSTON - In a first-of-its-kind finding, scientists at The University of Texas M. D. Anderson Cancer Center have discovered that exposure to the hepatitis B virus (HBV) may increase the risk of pancreas cancer. The study, reported in the Oct. 1 edition of the Journal of Clinical Oncology, also suggests that patients with this lethal form of cancer treated with chemotherapy may face danger of reactivation of their HBV........ ...
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Thursday, August 27, 2009
Post: Prevention and treatment of pancreatic cancer
A number of gastrointestinal tumors, including pancreas cancer, have been shown to overexpress the EGFR. The overexpression of EGFR correlates with rapidly progressive disease and poor prognosis. Targeting EGFR pathway as a potential therapeutic strategy for pancreas cancer has been developed. Erlotinib is a small molecule tyrosine kinase inhibitor that efficiently blocks EGFR. Preliminary results of phase III trial in pancreas cancer revealed an improvement in survival with the addition of erl...
Read More
Wednesday, August 26, 2009
Post: New drug substantially extends survival in pancreatic cancer
A new form of chemotherapy that destroys new blood vessels that grow around tumors has produced excellent results in a phase II trial of patients with inoperable pancreas cancer, scientists report at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm. European researchers led by Prof. Matthias Lhr from the Karolinska Institute reviewed the efficacy and safety of three different doses of cationic lipid complexed paclitaxel (EndoTAG-1) administered twice weekly, in...
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Tuesday, August 25, 2009
Post: Chemoradiation for pancreatic cancer better
The addition of the drug gemcitabine with chemoradiation for the therapy of patients who had surgery for pancreas cancer was linked to a survival benefit, eventhough this improvement was not statistically significant, as per a research studyin the March 5 issue of JAMA. Despite the potential benefits of surgically removing cancer involving the pancreas, there is a 50 percent to 85 percent rate of local relapse linked to liver and intra-abdominal failure and a 5-year survival of less than 20 per...
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Sunday, August 23, 2009
Post: Pancreatic cancer cells evade immune system
A protein that helps prevent a womans body from rejecting a fetus may also play an important role in enabling pancreas cancer cells to evade detection by the immune system, allowing them to spread in the body. Scientists at Jeffersons Kimmel Cancer Center in Philadelphia observed that the metastatic cancer cells in the lymph nodes of patients with pancreas cancer produce enough of the protein, IDO, to essentially wall-off the immune systems T-cells and recruit cells that suppress the immune sys...
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Saturday, August 22, 2009
Post: Apple compounds reduce risk of pancreatic cancer
Eating flavonol-rich foods like apples may help reduce the risk of pancreas cancer, says a team of international researchers. Quercetin, which is found naturally in apples and onions, has been identified as one of the most beneficial flavonols in preventing and reducing the risk of pancreas cancer. Eventhough the overall risk was reduced among the study participants, smokers who consumed foods rich in flavonols had a significantly greater risk reduction........ ...
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Friday, August 21, 2009
Post: Obesity, lack of exercise and pancreatic cancer
Obesity and aversion to exercise have become hallmarks of modern society and a new study suggests that a blood protein associated with these lifestyle factors may be an indicator for an increased risk of developing pancreas cancer. Scientists from the Dana Farber Cancer Institute report their findings in the August 15 issue of Cancer Research, a journal of the American Association for Cancer Research........ ...
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Thursday, August 20, 2009
Post: Protein May Indicate Pancreatic Cancer Risk
A protein that dwindles in response to obesity and a sedentary lifestyle may one day help doctors predict which people are at increased risk for pancreas cancer, new research by Dana-Farber Cancer Institute and collaborating researchers indicates. In a report in the Aug. 15 issue of Cancer Research, the researchers observed that, in a large study group, people with the lowest blood levels of a protein called IGFBP-1 were twice as likely to develop pancreas cancer as those with higher levels. Th...
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Wednesday, August 19, 2009
Post: New technique for earlier diagnosis of pancreatic cancer
A new optical technology, coupled with routine endoscopy, may enable doctors to detect the subtle tell-tale traces of early pancreas cancer, as per scientists at Northwestern University in Illinois. The optical technology, developed by biomedical engineers at Northwestern exposes cellular changes indicative of cancer in tissue near the pancreas that had previously been detectable only through intensive radiologic scanning or invasive surgery, two techniques that can put pancreas cancer patient...
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Tuesday, August 18, 2009
Post: vitamin B6. B12 and folate, may decrease pancreatic cancer risk
Scientists exploring the notion that certain nutrients might protect against pancreas cancer observed that lean individuals who got most of these nutrients from food were protected against developing cancer. The study also suggests this protective effect does not hold true if the nutrients come from vitamin supplements........ ...
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Monday, August 17, 2009
Post: A Pancreas Cancer Risk Model
People with a family history of pancreatic cancer now have a way to accurately predict their chance of carrying a gene for hereditary pancreatic cancer and their lifetime risk of developing the disease. Developed by Johns Hopkins Kimmel Cancer Center researchers, the novel computer software tool is designed to help genetic counselors and physicians decide who would most benefit from early screening........ ...
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Sunday, August 16, 2009
Post: Link Between Smoking AndPancreatic Cancer
Scientists at Michigan State University have added yet another piece to the puzzle that links cigarette smoking with cancer of the pancreas, one of the deadliest forms of cancer. In research reported in the recent issue of the International Journal of Cancer, MSUs James Trosko and his colleagues zeroed in on the mechanism by which a healthy cell turns malignant........ ...
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